Dr Bruce Kirkham

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Dr Bruce KirkhamDr. Bruce Kirkham qualified as a doctor in New Zealand before travelling to the United Kingdom to complete his postgraduate rheumatology training at Guy’s Hospital, including his MD thesis entitled “Immune Assessment and Immunotherapy in Rheumatoid Arthritis”.  This work involved the very early studies of monoclonal antibody therapy in rheumatoid arthritis.  

After working at the Walter and Eliza Hall Institute of Medical Research in Melbourne, Australia, in 1991 he became a Consultant Rheumatologist in Adelaide and subsequently in Sydney in 1995.  There he continued his work in clinical trials of new treatments and investigation of immune mechanisms, in particular IL-17 pathways, in inflammatory arthritis.  

He has been a Consultant Rheumatologist at Guy’s & St. Thomas’ NHS Foundation Trust since 2000, spending a year as Professor of Rheumatology, University of New South Wales, Sydney, in 2008-9.  In 2004, he developed the RACentre service to optimise the treatment of inflammatory arthritis, using treat-to-target strategies in routine care. In 2001 he was co-CI of the first study of infliximab in psoriatic arthritis.  This special interest continues with a close working relationship with the St John’s Institute of Dermatology, the largest centre for psoriasis in southern England.  His translational research interests are synovial correlates of disease with a focus on IL-17 immunology and cardiovascular complications of inflammatory arthritis.